Spectroscopy White Papers and Case Studies
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How To Make A Tissue Raman Measurement At 1064 nm
6/18/2019
The combination of improved Raman technology and the technique’s molecular sensitivity have led to a rise in Raman usage for a variety of applications including pharmaceutical, biomedical, industrial, and forensics. There remains, however, a struggle to extract useful Raman spectra from fluorescent and luminescent samples. For those users who require longer wavelengths such as 1064 nm, the only available option has been FT-Raman. Now, BaySpec’s new dispersive 1064 nm Raman spectrometers offer users a turn-key solution that combines the speed, sensitivity, and rugged design of traditional dispersive Raman instruments with the fluorescence avoidance of traditional FT-Raman instruments.
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Using SWIR Spectroscopy For Light Investigation And Analysis
6/12/2019
Examine the world of InGaAs linear arrays and detectors for NIR and SWIR spectroscopy and various applications and advantages of spectroscopy, including mineral analysis and material identification.
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Frictionless Precision Motion Control Based On Air Bearing Stages - Key Element In Coordinate Measuring And Surface Metrology Applications
8/23/2017
The performance of precision metrology equipment depends on highly accurate, repeatable, and controllable motion systems and position sensors. Air bearings have played a critical role in the development and construction of CMMs and other metrology tools.
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Minimizing Trade-Offs Between Spectral Smoothing And Resolution
3/28/2017
Boxcar smoothing is a convenient way to smooth noise in a spectrum, enabling peaks of interest to be more easily viewed, defined, and characterized for properties like peak intensity, center wavelength, and FWHM (full width half maximum).
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Noise In Spectrometers: Part 2
3/28/2017
Noise is an undesirable signal that is completely lacking in information or structure, and potentially takes away from the desired signal’s quality and accuracy. Part one of this two-part series discussed the sources of noise from a spectrometer and its experimental methods. This second part of the series takes the information gleaned in part one and uses it to measure low concentrations of sports drinks in a pool, develop a calibration curve, and determine the limit of detection for the spectrometer.
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Noise In Spectrometers: Part 1
3/24/2017
This application note is the first part in a series discussing the noise within spectroscopy systems used for ordinary applications, such as making sure the pool is clean after a large family gathering.
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CCD Cameras And Imaging Spectrographs Facilitate Acquisition Of Femtosecond Stimulated Raman Spectroscopy Data
11/9/2016
Characterizing surface-enhanced Raman spectroscopy (SERS) biosensors, or fluorescent dye molecules for in vivo bioanalyte detection, can be difficult due to the overwhelming isoenergetic fluorescence signal that makes it challenging to measure resonance Raman cross-sections for molecules.
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Medical Research With FLIR Thermal Imaging Cameras
8/23/2016
Tissue autofluorescence spectroscopy is utilized in a variety of biomedical research for differentiating between diseased and normal tissues. This app note discusses how researchers used FLIR cameras and ResearchIR software to work to gain a greater understanding of this surgical tool.
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NIR Spectroscopy Unbound
3/23/2016
Near-infrared (NIR) spectroscopy covers the wavelength space between ultraviolet-visible and infrared absorbance. With enormous potential for a variety of applications, NIR spectroscopy is much more accessible due to the availability of compact, high-value NIR spectrometers. This application note provides a brief introduction to NIR spectroscopy, and introduces the breakthrough Flame-NIR spectrometer from Ocean Optics for handheld and portable applications requiring NIR and chemometric analysis.
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NIR Spectroscopy Aids In The Diagnosis Of Neonatal Brain Injury
3/22/2016
An extensive set of spectroscopy-based methods have been developed over the past few years in order to facilitate more rapid and accurate detection and diagnosis of disease and injury. A British research group has recently designed and tested an NIRS system to assist in the diagnosis of neonatal brain injury. This new system measures the changes in tissue oxygenation and hemodynamics by estimating the changes in hemoglobin concentration. This application note presents a study on the diagnosis of neonatal brain injury through the use of CYRIL and quantitative near-infrared spectroscopy.