Spectroscopy White Papers and Case Studies

11. Characterization And Transformation Monitoring Of Polymorphs Of D-Mannitol With Raman Spectroscopy 6/18/2019

    Raman Spectroscopy is an ideal analysis technique for the analysis of these polymorphs with its vibrational spectroscopy, no need for sample preparation, and its non-destructive approach. 

12. Using A Multi-Wavelength Confocal Raman Microscope For Non-destructive Pharmaceutical Ingredient Analysis 6/18/2019

    Characterization of the active pharmaceutical ingredient (API) and its distribution and physical properties in commercial medicine is necessary in drug research and development. Raman spectroscopy is gaining popularity as nondestructive, non-invasive, fast spectrum acquisition, and high reproducibility. 

13. Polymorph And Ingredient Analysis With High-Resolution 1064 nm Dispersive Raman Spectroscopy 6/18/2019

    Polymorphism is crucial in the pharmaceutical industry because different polymorphs have different physical and chemical properties, such as chemical reactivity, solubility, stability, dissolution rate, and excipient compatibility in the formulation of medicines. Due to its importance, the screening of polymorph becomes necessary for drug research and development. In this application note, 1064 nm dispersive Raman is demonstrated as a viable, nondestructive method to identify polymorph and enable further component analysis on pharmaceutical tablets.

14. Explosives Identification With 1064 nm Dispersive Raman Spectroscopy 6/18/2019

    Near-IR Raman systems at 785 nm allow automated, non-contact identification of several explosive substances but are prone to interfering fluorescence. The 1064 nm dispersive Raman system offers reduced interference, higher prediction accuracy, and field-proven performance.

15. In Situ Raman Spectroscopic Measurements Of Metal Oxides Under High Temperature 6/18/2019

    Transition metal oxides are compounds composed of oxygen bound to transition metals used in various applications such as heterogeneous catalysts. To study the mechanism of the catalytic process as well as monitor and optimize the reaction conditions, multiple analytical methods such as XAS, NMR, and Raman spectroscopy have been investigated. Raman spectroscopy has been widely utilized in in-situ catalytic process monitoring with metal oxides, even achieved multi-technique characterization by combining with other instrumentations.

16. Graphene Analysis By Nomadic™ Raman Microscope 6/18/2019

    The BaySpec Nomadic™, a large-format Raman microscope, is an ideal tool for automatic wafer inspection, characterization, and Raman chemical imaging on large samples with a spatial resolution up to 1 µm, and it can accommodate large samples with a size up to 12 inches. In this application note, Raman spectroscopy used as a solution to identify and characterize graphine, with a direct analysis on its structural information.

17. Introduction To Portable Multi-Platform Raman System For Fuel Analysis 6/18/2019

    This application note introduces BaySpec’s transportable Agility product line featuring dispersive multi-wavelength Raman spectroscopy technology. Now liquid fuels’ measurements and analysis are simple tasks done in a few seconds, without sample contact or preparation.

18. Non-Destructive Red Wine Measurement With Dispersive 1064 nm Raman Spectroscopy 6/18/2019

    Despite advances, it remains a struggle to extract useful Raman spectra from fluorescent and luminescent samples. This app note discusses a non-destructive red wine measurement with dispersive 1064 nm Raman spectroscopy to determine its composition and contamination levels.

19. Using 1064 nm Dispersive Raman Systems For Analysis Of Petroleum Products 6/18/2019

    Raman spectroscopy is a non-invasive, highly sensitive technology that quantitatively probes and analyzes chemical compositions and structures without the need for sample preparation. In the past, this technology was not useful for petroleum and petroleum-based products due to their high levels of high level of photoluminescence that can overwhelm Raman signals in all visible wavelengths. This issue is now resolved by BaySpec’s line of 1064 nm excitation dispersive Raman systems that offer maximum reduction in fluorescence interference.

20. Using 1064 nm Dispersive Raman Systems In Biofuel And Plant Research 6/18/2019

    In the past, raman spectroscopy was not useful for plant-based samples due to their high levels of photosynthetic pigments as the fluorescent backgrounds can overwhelm Raman signals in all visible wavelengths. This issue is resolved by BaySpec’s line of 1064 nm excitation dispersive Raman systems.