Spectroscopy White Papers and Case Studies

  1. Aerial Hyperspectral Imaging: OCI Hyperspectral Imagers
    6/18/2019

    BaySpec’s OCI-UAV hyperspectral imagers are designed for use on small UAVs to monitor the details of spatial, temporal, and spectral representation of ground objects. This app note discusses benefits of these imagers offer and delivers example images for multiple topography analysis.

  2. Using 1064 nm Dispersive Raman For Ink And Paint Classification
    6/18/2019

    Raman spectroscopy is a non-invasive, highly sensitive technology that quantitatively probes and analyzes chemical compositions and structures without the need for sample preparation. In the past, this technology was not useful for forensics because most "real-world" samples have a vivid color, which can be a background emission (fluorescence) that could overwhelm Raman signals in all visible wavelengths. This issue is now resolved by BaySpec’s line of 1064 nm excitation dispersive Raman systems that offer maximum reduction in fluorescence interference.

  3. Characterization And Transformation Monitoring Of Polymorphs Of D-Mannitol With Raman Spectroscopy
    6/18/2019

    D-mannitol is a typical polymorphic crystalline solid that is widely used in pharmaceutical and food industries. Raman Spectroscopy is an ideal analysis technique for the analysis of these polymorphs with its vibrational spectroscopy, no need for sample preparation, and its non-destructive approach. In this application note, 1064 nm dispersive Raman is demonstrated as a viable, nondestructive method to identify polymorphs and apply process monitoring.

  4. Using A Multi-Wavelength Confocal Raman Microscope For Non-destructive Pharmaceutical Ingredient Analysis
    6/18/2019

    The characterization of the active pharmaceutical ingredient (API) and its distribution and physical properties in commercial medicine is necessary in drug research and development process in the pharmaceutical industry. Raman spectroscopy is gaining popularity due to its advantages as nondestructive, non-invasive, fast spectrum acquisition, and high reproducibility. BaySpec’s dispersive 1064 nm Raman spectrometers offer users a solution that combines the speed, sensitivity, and rugged design of traditional dispersive Raman instruments with the fluorescence avoidance of traditional FT-Raman instruments. This application note presents the results of a multi-wavelength confocal Raman microscope for non-destructive pharmaceutical ingredient analysis.

  5. Polymorph And Ingredient Analysis With High-Resolution 1064 nm Dispersive Raman Spectroscopy
    6/18/2019

    Polymorphism is crucial in the pharmaceutical industry because different polymorphs have different physical and chemical properties, such as chemical reactivity, solubility, stability, dissolution rate, and excipient compatibility in the formulation of medicines. Due to its importance, the screening of polymorph becomes necessary for drug research and development. In this application note, 1064 nm dispersive Raman is demonstrated as a viable, nondestructive method to identify polymorph and enable further component analysis on pharmaceutical tablets.

  6. Explosives Identification With 1064 nm Dispersive Raman Spectroscopy
    6/18/2019

    While traditional near-infrared Raman systems at 785 nm may allow automated, non-contact identification of several explosive substances, they are still prone to interfering fluorescence. The 1064 nm dispersive Raman system offers reduced interference and higher prediction accuracy, while preserving the rugged, field-proven architecture of conventional near-infrared Raman systems. This application note presents a study of explosive materials and subsidiary compounds analyzed using BaySpec’s 785 nm and 1064 nm dispersive Raman systems.

  7. In Situ Raman Spectroscopic Measurements Of Metal Oxides Under High Temperature
    6/18/2019

    Transition metal oxides are compounds composed of oxygen bound to transition metals used in various applications such as heterogeneous catalysts. To study the mechanism of the catalytic process as well as monitor and optimize the reaction conditions, multiple analytical methods such as XAS, NMR, and Raman spectroscopy have been investigated. Raman spectroscopy has been widely utilized in in-situ catalytic process monitoring with metal oxides, even achieved multi-technique characterization by combining with other instrumentations.

  8. Graphene Analysis By Nomadic™ Raman Microscope
    6/18/2019

    The BaySpec Nomadic™, a large-format Raman microscope, is an ideal tool for automatic wafer inspection, characterization, and Raman chemical imaging on large samples with a spatial resolution up to 1 µm, and it can accommodate large samples with a size up to 12 inches. In this application note, Raman spectroscopy used as a solution to identify and characterize graphine, with a direct analysis on its structural information.

  9. Introduction To Portable Multi-Platform Raman System For Fuel Analysis
    6/18/2019

    Raman spectroscopy is a non-invasive, highly sensitive technology that quantitatively probes and analyzes chemical compositions and structures without the need for sample preparation. In the past, this technology was not useful for plant-based and petroleum-based products due to their high levels of high level of fluorescence that can overwhelm Raman signals in all visible wavelengths. This application note introduces BaySpec’s transportable Agility™ product line featuring dispersive multi-wavelength Raman spectroscopy technology. Now liquid fuels’ measurements and analysis are simple tasks done in a few seconds, without contacting, or any preparation of the sample.

  10. Non-Destructive Red Wine Measurement With Dispersive 1064 nm Raman Spectroscopy
    6/18/2019

    The combination of improved Raman technology and the technique’s molecular sensitivity have led to a rise in Raman usage for a variety of applications including pharmaceutical, biomedical, industrial, and forensics. There remains, however, a struggle to extract useful Raman spectra from fluorescent and luminescent samples. BaySpec’s new dispersive 1064 nm Raman spectrometers offer users a turn-key solution that combines the speed, sensitivity, and rugged design of traditional dispersive Raman instruments with the fluorescence avoidance of traditional FT-Raman instruments. This application note presents the results of a non-destructive red wine measurement with dispersive 1064 nm Raman spectroscopy to determine its composition and contamination levels.