Microscopy News
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New Method Could Democratize Deep Learning-Enhanced Microscopy
3/8/2021
Deep learning is a potential tool for scientists to glean more detail from low-resolution images in microscopy, but it’s often difficult to gather enough baseline data to train computers in the process. Now, a new method developed by scientists at the Salk Institute could make the technology more accessible—by taking high-resolution images, and artificially degrading them.
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How Photoblueing Disturbs Microscopy
2/26/2021
The latest developments in fluorescence microscopy make it possible to image individual molecules in cells or molecular complexes with a spatial resolution of up to 20 nanometres. However, under certain circumstances, an effect occurs that falsifies the results: the laser light used can cause very reactive oxygen molecules to form in the sample. These can then damage the fluorescent dyes used to such an extent that they no longer fluoresce. Among microscopy experts, this effect is known as photobleaching.
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New Microscopy Concept Enters Into Force
2/5/2021
The development of scanning probe microscopes in the early 1980s brought a breakthrough in imaging, throwing open a window into the world at the nanoscale. The key idea is to scan an extremely sharp tip over a substrate and to record at each location the strength of the interaction between tip and surface.
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Research Could Dramatically Lower Cost Of Electron Sources
2/1/2021
Rice University engineers have discovered technology that could slash the cost of semiconductor electron sources, key components in devices ranging from night-vision goggles and low-light cameras to electron microscopes and particle accelerators.
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Fluorescence Microscopy At Highest Spatial And Temporal Resolution
1/14/2021
Only a few years ago, an ostensibly fundamental resolution limit in optical microscopy was superseded - a breakthrough which in 2014 led to the Nobel Prize in Chemistry for super-resolution microscopy.
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Nanocylinder Vibrations Help Quantify Polymer Curing For 3D Printing
12/10/2020
In a step toward making more accurate and uniform 3D-printed parts such as personalized prosthetics and dental materials, researchers at the National Institute of Standards and Technology (NIST) have demonstrated a method of measuring the rate at which microscopic regions of a liquid raw material harden into a solid plastic when exposed to light.
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Record Resolution In X-Ray Microscopy
12/4/2020
Researchers at FAU, the Paul Scherrer Institute in Switzerland and other institutions in Paris, Hamburg and Basel, have succeeded in setting a new record in X-ray microscopy. With improved diffractive lenses and more precise sample positioning, they were able to achieve spatial resolution in the single-digit nanometre scale.
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Scientists Invent A New Type Of Microscope That Can See Through An Intact Skull
12/3/2020
Non-invasive microscopic techniques such as optical coherence microscopy and two-photon microscopy are commonly used for in vivo imaging of living tissues. When light passes through turbid materials such as biological tissues, two types of light are generated: ballistic photons and multiply scattered photons.
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Controlling Fully Integrated Nanodiamonds
11/23/2020
Using modern nanotechnology, it is possible nowadays to produce structures which have a feature sizes of just a few nanometres. This world of the most minute particles – also known as quantum systems – makes possible a wide range of technological applications, in fields which include magnetic field sensing, information processing, secure communication or ultra-precise time keeping.
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An Electrical Trigger Fires Single, Identical Photons
10/8/2020
Secure telecommunications networks and rapid information processing make much of modern life possible. To provide more secure, faster, and higher-performance information sharing than is currently possible, scientists and engineers are designing next-generation devices that harness the rules of quantum physics.