Microscopy White Papers and Case Studies

  1. Optical Filter Solutions

    Iridian Spectral provides optical filter solutions with proprietary thin-film design deposition and manufacturing technology in order to deliver durable and high-performance optics for point-of-care medical diagnostics, Raman spectroscopy, fluorescence spectroscopy, MID IR applications, biophotonics, telecommunications, astronomy, and space.

  2. Optical Filters For Raman Analysis: Finding The Needle In The Haystack

    Most Raman microscopy applications seek to maximize access to the Raman fingerprint of the molecule of interest, requiring filters that provide “more signal with less background.” This article discusses optical filters for Raman analysis, addressing filters for both bench-top and portable Raman applications.

  3. Overcoming Scattering Media Challenges In Multi-Photon Microscopy

    A major problem standard MPM faces is correcting for scattering media. To solve this issue, Dr. Meng Cui at the Howard Hughes Medical Institute has recently pioneered Super Penetration Multi-Photon Microscopy (S-MPM) at the Cui Lab. He has successfully reported on focusing light through static and dynamic strongly scattering media using Boston Micromachines’ segmented 492-DM. By using the iterative multi-photon adaptive compensation technique (IMPACT), he since reported new results on in vivo fluorescence microscopy, providing a unique solution to noninvasive brain imaging.

  4. PentaVac™ Vacuum Technology: Scientific CCD Applications

    CCD imaging sensors are used extensively in high-end imaging applications, enabling acquisition of quantitative images with both high (spatial) resolution and high sensitivity. By Dr. Geoff Martin, Principal Systems Engineer, Raptor Photonics Ltd

  5. Isotropic Four-Dimensional Imaging with Dual-View Plane Illumination Microscopy

    ASI recently developed a dual inverted selective plane illumination microscopy system (diSPIM) that offers several advantages over conventional microscopy systems. This paper explains those advantages in great detail and contains application examples of how the system has been successfully used.

  6. Piezo Mechanisms In Optics And Laser Technology

    Laser technology is crucial for the advancement of many high tech fields from aerospace to medical diagnostics. By Stefan Vorndran, Scott Jordan, Steffen Arnold, PI (Physik Instrumente)

  7. An Introduction To Digital Microscopy Imaging

    As fun as taking pictures may be, it is the professional analysis of samples that really counts. This article discusses key concepts of digital microscopy imaging systems and how these concepts contribute to a professional presentation of your work. By SPOT Imaging Solutions, a division of Diagnostic Instruments, Inc.

  8. PI Products For Microscopy

    This brochure includes information on PI’s offerings as they relate to microscopy applications.

  9. Piezo and Motion Control Solutions for Medical Applications

    PI offers Piezo and motion control solutions for microdosing, biohandling, computer aided surgery, microscopy, and other medical applications.

  10. 3 Trends In Biological Imaging — And Their Impact On Microscope Automation And Control

    The field of biological imaging is constantly evolving, driven forward by the increasingly complex and technologically sophisticated demands of the research community. As microscopy and other imaging techniques change, so too must the motion control systems that enable them. Photonics Online recently had the opportunity to talk with John Zemek, executive director of Applied Scientific Instrumentation. ASI manufactures sub-micron micropositioning hardware for laboratory and microscope automation and OEM systems. Zemek discusses the trends in biological imaging that are having the biggest influence on positioning system design, and what factors you should consider when evaluating such technology for your specific application.