Microscopy White Papers and Case Studies

  1. Understanding Microscopes And Objectives 6/26/2023

    A microscope is an optical device used to image an object onto the human eye or a video device. To understand these complex optical devices, consider a microscope's components, key concepts and specifications, and applications.

  2. Atomic Force Microscopes And Treating … Baldness? 6/23/2023

    Atomic force microscopes, first developed in the mid-1980s by Gerd Binig, Calvin Quate, and Christoph Gerber, gather information by “feeling” the surface with a mechanical probe. Today, AFM serves as a reliable and high-precision measurement tool for analyzing surfaces. They also played a role in discovering a potential treatment for baldness.

  3. EMCCD vs sCMOS - Cameras For Confocal Microscopy 6/21/2023

    When is it then appropriate to use an EMCCD camera or an sCMOS camera as a detector for spinning disk confocal microscopy – the biologist’s technique of choice for fast, multi-dimensional live-cell imaging? 

  4. LASER World Of Photonics Celebrates 50 Years Of Laser 6/7/2023

    Fifty years ago, LASER 73 brought together about 100 exhibitors to marvel at all photonics had to offer. Now, tens of thousands are flocking to Munich to attend LASER World of PHOTONICS, one of photonics’ leading trade fairs.

  5. Defense + Commercial Sensing: Exploring The Latest Innovations In Imaging, Sensing, And Photonic Technologies 4/11/2023

    Over the past 68 years, SPIE has been connecting, engaging, and serving its global constituency of more than 258,000 people from 184 countries. A big part of meeting that mission is accomplished by hosting conferences and exhibitions and, at the end of the month, SPIE will be hosting a big one: The Defense + Commercial Sensing conference and exhibition.

  6. Sub 50 Femtosecond Pulse Lasers For Gentler Multiphoton Microscopy 1/25/2023

    Finding the ideal ultra-fast laser source for a multiphoton imaging setup is not trivial. It is a fine balance between peak power, pulse energy and laser wavelength.

  7. Improving The Sensitivity Of Multicolor Microscopy Techniques 12/20/2022

    Single molecule fluorescence (or Förstner) resonance energy transfer (smFRET) is used to measure distances at the 1-10 nanometer scale in single molecules, typically biomolecules.

  8. SL160 Slide Loader Brochure 10/3/2022

    Speed up your work with reliable sample handling. The Prior SL160 Slide Loader is a fast and easy-to-use system to automate your slide scanning process.

  9. Confocal Microscopy 101 9/26/2022

    Confocal microscopy is a type of fluorescence microscopy that uses a laser to excite fluorescence from fluorophores used to label different subsets of a specimen.

  10. Intro To Multiphoton Microscopy 9/23/2022

    Multiphoton microscopy is ideal for capturing high-resolution 3D images with reduced photobleaching and phototoxicity compared to traditional confocal microscopy techniques.