Mobius Photonics Delivers Upgraded Fiber Laser For STED Microscopy
Mobius Photonics, an innovative producer of short pulsed fiber laser sources (IR, green, and UV laser), has delivered an upgraded fiber laser that produces visible light with 20MHz pulse repetition rate to a leading European research institute. Tailored for stimulated emission depletion (STED) microscopy experiments, the laser has been designed to dramatically improve imaging speed over prior STED set ups that used 1MHz Mobius lasers.
STED microscopy is a noninvasive microscopy technique that provides users with ultra-high-resolution images of biological samples. However, its application has been hampered by the availability of suitable light sources, as current technologies are limited by complexity, power, repetition rate, or wavelength. Accordingly, research has focused on developing a system based on a novel laser source that could enhance the technique's capabilities—specifically, the ability to generate ultra-high-resolution images with rapid throughput and to use fluorescent markers of choice.
"Our previous laser enabled STED researchers to access a wider variety of markers in their experiments and to generate very detailed images, but imaging speed was still an issue," said Manuel Leonardo, co-founder and vice president of Mobius Photonics. "This new system has been designed to produce images many times faster than previous set-ups, putting us in a more competitive position with today's commercial STED systems."
The Mobius Photonics laser is based on pulsed master-oscillator, fiber-power-amplifier (MOFPA) architecture. A versatile source, it provides diffraction-limited operation over a range of user-adjustable settings.
About Mobius Photonics
Founded in 2005, Mobius Photonics, Inc. produces fiber-based laser sources for applications ranging from material processing for solar cell manufacturing, semiconductor fabrication and assembly, and flat panel display manufacturing, to scientific uses such as STED microscopy. The Mobius Photonics team combines in-depth understanding of customer needs with manufacturing experience, and pushes the state-of-the-art by working in close collaboration with suppliers and customers around the world.
For more information, visit www.mobiusphotonics.com.
SOURCE: Mobius Photonics