MICROSCOPY WHITE PAPERS AND CASE STUDIES

Confocal Microscopy Evolves With AO Tunable Filters Acousto-optical tunable filter (AOTF) technology is growing to replace conventional and cumbersome mechanical techniques within biomedical applications for confocal microscopy. Benefits of using AO tunable systems include electronic control, configurable drivers for improving operator flexibility, feedback stabilizing systems to maintain wavelength stability for all environmental conditions, and custom-grown tellurium dioxide crystals to ensure...  Continue Reading...
Comparison Of Scientific Cameras For Fluorescence Microscopy Raptor Photonics recently compared the performance of four of their scientific cameras in fluorescence microscopy. Each camera utilized a different sensor technology, EMCCD, sCMOS and CCD under similar conditions in order to find the advantages of each one.  Continue Reading...
Air Bearing FAQs
Air Bearing FAQs This blog article presents questions and answers on air bearing positioning equipment.  Continue Reading...
Super-Resolution Optical Microscopy, Nanoscopy, And Nanopositioning Motion Control
Super-Resolution Optical Microscopy, Nanoscopy, And Nanopositioning Motion Control This article presents the new frontier for super-resolution optical microscopy, nanoscopy, and nanopositioning motion control.  Continue Reading...
Automation And Microscopy: Faster Test And Measurement The world of nano-technology now uses the concept that constant velocity will get you to the destination faster than constantly stopped traffic. One technique puts this concept into practice through the use of a fast nano-focus device based on a piezo-ceramic actuator embedded in a flexure guided lens positioning mechanism from PI. This technique allows a comprehensive examination of micro well plates within seconds. This application note...  Continue Reading...
Compact, Lens-Free Microscope Demo Kit Adapts To User Applications
Compact, Lens-Free Microscope Demo Kit Adapts To User Applications Lens-free microscopy enables an abundance of applications to which traditional microscopes are less amenable. Examples include particle monitoring in a cleanroom environment or cell monitoring with the microscope integrated in the biotech tool. Built on earlier prototypes, imec’s lens-free digital microscope is offered as a ready-to-use evaluation kit for life sciences and industrial applications. This demo kit allows companies to try out...  Continue Reading...
Optical Components for SWIR Imaging
Optical Components for SWIR Imaging This application note provides information on the benefits of SWIR imaging in harsh or low-light level conditions, and PG&O's capabilities in manufacturing optical components for SWIR imaging.  Continue Reading...
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MICROSCOPY PRODUCTS

Compact sCMOS Camera: pco.panda Compact sCMOS Camera: pco.panda

The new pco.panda is a state-of-the-art sCMOS sensor camera system designed to provide high quantum efficiency with the lowest dark noise for a number of applications, including live cell microscopy, single molecule detection, bio- and chemi-luminescence, GSDIM, PALM, STORM, SPIM, and more. It also is housed in a compact package – just 65 mm3.

Q-Motion® Server Controller Q-Motion® Server Controller

PI’s new Q-Motion® Server Controller is designed as a digital servo controller for positioning systems with piezo inertia drives. It is a benchtop device with options for control cabinet mounting, and has three channels with integrated power amplifiers and an interpolator. The device features a point-to-point motion and actuator mode for nanometer precision positioning at the target position.

NEXACT<sup>®</sup> PiezoWalk<sup>®</sup> Stepping Drive With Subnanometer Encoder Resolution: N-565 NEXACT® PiezoWalk® Stepping Drive With Subnanometer Encoder Resolution: N-565

The N-565 is an ultra-precision linear positioner stage with NEXACT® PiezoWalk® technology, and designed with a subnanometer encoder resolution for high-end applications in bio-nanotechnology, fiber-optics, microscopy, semiconductor testing, metrology, and scientific research in beamlines and laser labs. With long 13 mm, 26 mm, or 52 mm travel ranges, high forces, and stiffness, this stepping drive does not subject to sliding friction or wear.

Near-Field Scanning Optical Microscope: MCL-NSOM Near-Field Scanning Optical Microscope: MCL-NSOM

The MCL-NSOM is a fully operational near-field scanning optical microscope manufactured on Mad City Labs’ versatile RM21™ inverted optical microscope. This instrument is designed to allow users to convert between NSOM, SPM, and fluorescence optical microscopy techniques.

RM21™ Microscope For Fluorescence Microscopy RM21™ Microscope For Fluorescence Microscopy

Mad City Labs’ RM21™ Microscope is an adaptable microscopy platform that is designed to allow direct access to the entire optical pathway, and is capable of precision alignment in the X, Y, and Z axes. The Z-axis objective lens holder is precision aligned with the optical axis of the platform and can hold a single objective lens. The RM21 microscope is compatible with Mad City Labs closed loop nanopositioning stages making it suitable for nanometer precision applications such as super resolution microscopy and other single molecule microscopy techniques.

XYZ Nanopositioning System: Nano-LPMW XYZ Nanopositioning System: Nano-LPMW

The Nano-LPMW is a unique XYZ axis nanopositioning system designed to hold multiwall plates, slides, dishes, and environmental chambers. This low profile positioner has an extra-large center aperture with a 200 micron range of motion on all three axes. It is easily integrated into existing inverted optical microscopes and is compatible with numerous microscope stages.

MicroMirror TIRF System MicroMirror TIRF System

Mad City Labs offers the MicroMirror TIRF system as a new single molecule imaging instrument composed with high precision, high stability nanopositioning and microscopy technologies. Using the technique of micro-mirror total internal reflection fluorescence (TIRF) microscopy, this system is designed for studying the ordered assembly and function of multi-component biomolecular machines.

Scientific CMOS Cameras: pco.edge Camera Link HS (CLHS) 4.2 And 5.5 Scientific CMOS Cameras: pco.edge Camera Link HS (CLHS) 4.2 And 5.5

The new pco.edge Camera Link HS (CLHS) series is comprised of cameras that combine sCMOS technology with an ultra-fast Camera Link HS interface. These cameras are designed to provide low latency, low jitter, real-time signals between a camera and frame grabber while carrying image data, control data, and trigger events. CLHS is designed from a system point of view which fully exploits CMOS sensor technology while remaining cost effective, and providing reliable data demanded by customers.

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MICROSCOPY SUPPLIERS

BaySpec Inc. BaySpec Inc.

BaySpec, Inc., founded in 1999 with 100% manufacturing in the USA (San Jose, California), is a vertically integrated spectral sensing company. The company designs, manufactures and markets advanced spectral instruments, including UV-VIS-NIR-SWIR spectrometers, benchtop and portable NIR/SWIR and Raman analyzers, confocal Raman microscopes, hyperspectral imagers, mass spectrometers, and OEM spectral engines and components, for the R&D, biomedical, pharmaceuticals, chemical, food, semiconductor, health monitoring, human & animal medical devices, and the optical telecommunications industries.

Canon USA, Inc. Optoelectronic Components Canon USA, Inc. Optoelectronic Components

Canon U.S.A., Inc., is a leading provider of business-to-business, industrial and consumer digital and optical imaging solutions to the United States, Latin America and the Caribbean (excluding Mexico) markets with an increasing intent for more customized, localized products.

FLIR Systems, Inc FLIR Systems, Inc

Infrared Cameras|Infrared Imaging Subsystems|Thermal Cameras|Infrared Camera Subsystems|Ruggedized Infrared Cameras|Visual Inspection, Thermal|Infrared Surveillance|Video Inspection Systems, Thermal|Infrared Detectors|Thermal Sensors|Night Vision Cameras|Night Vision Systems|Detectors, Infrared|Detectors, Heat|Infrared Imagers|Infrared Equipment|Infrared Sensors|Security Systems, Infrared|Thermal Imaging Systems|Military Infrared Sensors|Integrated Detective Assemblies, Infrared|Optical Inspection Systems,Thermal|Thermal Camera Systems|Night Vision Components|Infrared Video Cameras|Data Acquisition Software,Infrared|Focal Plane Arrays|Machine Vision Systems, Infrared|Infrared Industrial Detectors|Infrared Inspection Systems|Automated Inspection, Infrared

Gooch & Housego PLC Gooch & Housego PLC

Gooch & Housego provides complete optical system design, engineering and manufacturing services to the aerospace & defense, industrial, life sciences and scientific research sectors, based upon the following key enabling photonic technologies: Acousto-Optics, Crystal Optics Electro-Optics, Fiber Optics and photonic packaging, Non-Linear Optics, Precision Optics including optical polishing and coatings, as well as light measurement instrumentation and services, spectral Imaging & synthesis.

Hamamatsu Corporation Hamamatsu Corporation

Photomultiplier Tubes|Arc Lamp|Photo Multiplier|Spectroscopy Systems

Iridian Spectral Technologies Iridian Spectral Technologies

Iridian Spectral Technologies is a diversified optical filter manufacturer that is an international leader in filter design and manufacture especially for application in the fields of fiber optic communications, optical spectroscopy, 3D entertainment, and in aerospace. Iridian Spectral Technologies was ranked as one of the top 150 high technology companies in Canada in the 2011 and 2012 Branham300 rankings and won the 2010 Canada Export Achievement Award for the province of Ontario sponsored by Profit magazine together with Export Development Corporation (EDC). Iridian Spectral Technologies is a global supplier with distributors in many countries particularly in Asia.

Mad City Labs, Inc. Mad City Labs, Inc.

Mad City Labs, Inc. is the leading US manufacturer of precision piezo based nanopositioning stages and nano-instrumenation.  We manufacture high performance motion control instrumentation including our innovative closed loop nanopositioning systems, high stability microscopy platforms, low cost probe microscopy and metrology solutions.  Our instruments are suitable for super resolution microscopy, metrology, imaging, photonics, interferometry and astronomy.

PCO-TECH Inc. PCO-TECH Inc.

PCO-TECH Inc., founded in 1986, is a manufacturing, sales and marketing organization offering photonic instrumentation and complete systems throughout the world

Photron, Inc. Photron, Inc.

Photron was founded in 1974 to provide manufacturing, sales and service of professional film and video equipment and photo-instrumentation

PI (Physik Instrumente) LP PI (Physik Instrumente) LP

PI (Physik Instrumente) provides the world’s broadest range of precision motion technologies for both micro- and nano-precision applications. PI is the world’s first and largest manufacturer of piezoelectric nanopositioning technology.  Started 4 decades ago as a supplier to research labs and universities, the company has grown into a business of 700+ employees and more than $100 million in global sales.

Precision Optics Corporation Precision Optics Corporation

For over 30 years, Precision Optics Corporation has provided state-of-the-art optical designs, components and complete optical systems for medical, biomedical, military (ITAR complainant) and industrial applications. As next generation techniques in these areas have advanced to use smaller and less invasive tools and equipment, Precision Optics responded with microprecision™ optical technology to provide components, assemblies, and products with sizes on the order of one millimeter and smaller.

Raptor Photonics Limited Raptor Photonics Limited

Raptor Photonics Limited, founded in 2006, is a global leader and manufacturer of high performance, industrial-grade and rugged low light digital & analogue cameras. Raptor specialises in complete cameras and core engine solutions using EMCCD, Scientific CMOS, SWIR and Vis-SWIR sensor technology.

Sensors Unlimited - UTC Aerospace Systems Sensors Unlimited - UTC Aerospace Systems

UTC Aerospace Systems (Sensors Unlimited Products), is the world’s leading manufacturer of indium gallium arsenide (InGaAs)-based imaging products. As renowned experts in shortwave infrared (SWIR) imaging, Sensors Unlimited, Inc. introduced the world to the concept of imaging in the shortwave IR spectrum with simple, compact, and uncooled cameras.

Xenics Xenics

Xenics is a well established and rapidly growing high-tech company about to enter exciting new fields of IR products and applications, serving the markets with excellent products and a strong technology background.

Zygo Corporation Zygo Corporation

Supplier of precision optics including extreme precision aspheres and freeform, meter-class flats and windows in common and exotic materials. Full electro-mechanical-optical design/prototype and manufacturing capabilities for medical, defense, military, ISR, semiconductor and industrial technology research.

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MICROSCOPY NEWS

  • STReM Technique Captures High-Speed, Super-Resolution Images Without Need For A Fast Camera
    STReM Technique Captures High-Speed, Super-Resolution Images Without Need For A Fast Camera

    Rice University researchers have refined a Nobel Prize-winning microscopy technique to capture fluorescing molecules at a frame rate 20 times faster than other laboratory cameras.

  • PI Launches 2nd Generation PInano® Piezo Stage For SR Microscopy
    PI Launches 2nd Generation PInano® Piezo Stage For SR Microscopy

    PI has recently released a 2nd generation of its successful PInano® product line of high resolution XY/XYZ multi-axis positioning systems. The digital servo piezo controller offers the advantage of higher linearity, simple operation, and easy access to advanced features in comparison to conventional analog piezo controllers. It provides responsive real-time tracking, and it supports PI's unique Fast Focus & Freeze capability, where the unit can be bumplessly switched from external (focus) sensor to internal (capacitive, SGS or piezoresistive) sensor, allowing precise, calibrated, stable motions with respect to the focal plane.

  • Qioptiq mag.x system 125 Now Optimized For 35 mm Camera Format Sensors
    Qioptiq mag.x system 125 Now Optimized For 35 mm Camera Format Sensors

    Qioptiq, an Excelitas Technologies® Company, recently introduces the new 1.73x Tube Lens as a widely desired addition to the mag.x system 125. Representing a new class of optical systems that enable microscope-like resolution with wide fields-of-view to support modern high-resolution sensors, the 1.73x Tube Lens makes the mag.x system 125 a perfect match for sensors with the 35 mm camera format.

  • High Power Violet Lasers Improve Cytometry And Confocal Microscopy Applications
    High Power Violet Lasers Improve Cytometry And Confocal Microscopy Applications

    A new, high power, ultra-compact, violet laser from Coherent, Inc. will provide improved performance for numerous short wavelength applications, including examples in life sciences, where it will enable brighter confocal imaging and faster flow cytometry throughput rates.

  • Nanometer Precision 3-Channel Controller For Miniature Piezo Inertia Drives And Actuators
    Nanometer Precision 3-Channel Controller For Miniature Piezo Inertia Drives And Actuators

    PI (Physik Instrumente) L.P. recently announced the newest digital servo controller with 3-channels, offering greater flexibility for miniaturized precision positioning and handling tasks. Applications include precision alignment and automation, semiconductor technology, photonics, bio-nano-technology, metrology, microscopy, micro-manipulation.

  • New PI Low-Cost, Compact, And Smooth Running Stepper/Servo Motor Solution
    New PI Low-Cost, Compact, And Smooth Running Stepper/Servo Motor Solution

    PI offers a new L-406 compact linear stage delivers performance and reliability at minimized cost. It has applications in research and industrial applications, including bio-nanotechnology, microscopy, micromanipulation, inspection and metrology, beamline systems, and photonics instrumentation.

  • Xenics At DCS: Top-Notch Space Technology Serving The Industry
    Xenics At DCS: Top-Notch Space Technology Serving The Industry

    Xenics will attend SPIE DCS 2016 with a host of new developments, among them the first performance results of a family of high-resolution SWIR line-scan arrays that work up to 400 KHz of line rate. These arrays serve space applications that require high resolution line-scan arrays as well as medical (3D SD-OCT) and industrial applications that require high line rates. . Xenics will exhibit in Booth 523 at the Baltimore Convention Center.

  • New Laser System Captures Two Types Of Microscopy Images With One Light Source
    New Laser System Captures Two Types Of Microscopy Images With One Light Source

    Researchers have designed a simple new laser system that allows the acquisition of two types of microscopy images with a single light source.

  • New Open Source Software For High Resolution Microscopy
    New Open Source Software For High Resolution Microscopy

    Bielefeld physicists report their new development in Nature Communications With their special microscopes, experimental physicists can already observe single molecules.

  • ORNL–NIST Team Explores Nanoscale Objects And Processes With Microwave Microscopy
    ORNL–NIST Team Explores Nanoscale Objects And Processes With Microwave Microscopy

    When lots of energy hits an atom, it can knock off electrons, making the atom extremely chemically reactive and initiating further destruction. That’s why radiation is so dangerous. It’s also why high-resolution imaging techniques that use energetic electron beams and X-rays can alter, even obliterate, the samples they explore.

  • Excelitas' X-Cite 120LEDBoost For Fluorescence Microscopy

    Excelitas Technologies Corp. introduces X-Cite 120LEDBoost to replace their popular X-Cite 120LED broad-spectrum solution. With the same key features and mercury-free benefits as its predecessor, X-Cite 120LEDBoost delivers 40% more power for improved fluorophore excitation.

  • New High-Speed Piezo Z-Stage And Digital Controller Value  Packages For Microscopy And Metrology
    New High-Speed Piezo Z-Stage And Digital Controller Value Packages For Microscopy And Metrology

    PI recently released several controller & stage value packages for microscopy and metrology applications. These affordable systems consist of a PIFOC® high performance fast piezo focus mechanism and a compact digital servo controller. These outstanding packages deliver higher performance at lower cost.

  • New ORNL Device Combines Power Of Mass Spectrometry, Microscopy
    New ORNL Device Combines Power Of Mass Spectrometry, Microscopy

    A tool that provides world-class microscopy and spatially resolved chemical analysis shows considerable promise for advancing a number of areas of study, including chemical science, pharmaceutical development and disease progression.

  • Excelitas Technologies® Corp. Unveils New LED Illuminator For Microscopy
    Excelitas Technologies® Corp. Unveils New LED Illuminator For Microscopy

    Excelitas Technologies Corp. recently announced a new multi-wavelength LED fluorescence illuminator optimized for microscopy imaging and detection applications. The new X-Cite TURBO provides maximum excitation power for all standard color wavelengths.

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MICROSCOPY VIDEOS

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