Article | December 10, 2008

Article: Recent Approaches To 'Super-Resolution' Microscopy Utilizing Camera Detection

Source: Andor Technology PLC
By Dr. Marcin Barszczewski Applications Specialist, Imaging and Dr. Colin Coates Market Development Manager, Imaging, Andor Technology, Belfast, Northern Ireland

Abstract
In this article, we describe some novel camera-based approaches which enable the cell biologist to break through the diffraction-limited spatial resolution of classical light microscopy, enabling much finer sub-cellular detail to be elucidated than was previously possible. The role of ultra-sensitive, rapid readout cameras is proving central to the ability to drive these methods faster, particularly critical to realize the goal of super-resolution imaging of dynamic processes in living cells.

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