Newsletter | October 14, 2021

10.14.21 -- Precision Motion And Microscopy In Biophysics Applications

 
Precision Motion And How To Achieve It
 

Moving from micron-level research to the nanoscale forces researchers to better understand their own experiments, as well as their own actions’ contributions to passive factors that undermine precision. With this understanding comes recognition that simple modifications to an experiment or instrumentation can assist in achieving their precision goals without the intervention of additional processing.

Is A DIY Microscope For You?
 
Whether modifying existing instrumentation or building a new tool from the ground up, a meticulous process is as critical as the functional result. This article helps one determine whether a do-it-yourself (DIY) microscope is the appropriate solution for your application. It then details how to procure an instrument that meets both current and future application needs while remaining cost-effective.
Optical Micromirrors Reveal The Secrets Of Cell Membranes
 
Progress in understanding the lipid bilayer — a two-molecule thick oily barrier that protects all living cells — has been dramatic over the past 100 years. But puzzles remain to be solved, such as how these membrane proteins navigate the oily lipid bilayer to go about their work.
Poking And Prodding The Molecules Of Life
 
Applying physics to the properties and underlying structures of the molecules of life offers an insight into the mechanisms that make living beings tick. The scientific community has developed a powerful toolbox of methods to probe these interactions over the past two decades, uncovering previously hidden information about the structure, dynamics, and function of individual biomolecules.
Solutions
RM21 MicroMirror TIRF Microscope

The MicroMirror TIRF microscope is a unique single molecule microscope. Spatial separation of the excitation and emission beams and the use of broadband micromirrors leads to superior signal-to-noise ratios for multi-wavelength TIRF microscopy. The open access to the excitation and emission optical pathways makes this the ideal platform to implement a range of biophysical techniques simultaneously. 

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