Overcoming Scattering Media Challenges In Multi-Photon Microscopy

By Boston Micromachines

A major problem standard MPM faces is correcting for scattering media. To solve this issue, Dr. Meng Cui at the Howard Hughes Medical Institute has recently pioneered Super Penetration Multi-Photon Microscopy (S-MPM) at the Cui Lab. He has successfully reported on focusing light through static and dynamic strongly scattering media using Boston Micromachines’ segmented 492-DM. By using the iterative multi-photon adaptive compensation technique (IMPACT), he since reported new results on in vivo fluorescence microscopy, providing a unique solution to noninvasive brain imaging.